Here is the article I read in past few days. I typed some related paragraphs here.
Fortier and Travis Stem Cell Research & Therapy 2011,2:9
http://stemcellres.com/content/2/1/9
Stem cells in veterinary medicine
Abstract
The stem cell field in veterinary medicine continues to evolve rapidly both experimentally and clinically. Stem cells are most commonly used in clinical veterinary medicine in therapeutic applications for the treatment of musculoskeletal injuries in horses and dogs. New technologies of assisted reproduction are being developed to apply the properties of spermatogonial stem cells to preserve endangered animal species. The same methods can be used to generate transgenic animals for production of pharmaceuticals or for use as biomedical models. Small and large animals species serve as valuble modles for preclinical evaluation of stem cell application in human beings and in veterinary patients in ares such as spinal cord injury and myocardial infarction. However, these application have not been implemented in the clinical treatment of veterinary patients. Reviews on the use of animal models for stem cell research have been published recently. Therefore, in this review, animal model research will be reviewed only in the context of supporting the current clinical application of stem cells in veterinary medicine.
Below is the paragraphs regards in dog arthritis:
Adipose-derived stromal vascular fraction (AD-SVF) cells
The currently available technique uses a mixture of cells derived from adipose tissue surgically excised from horses of dogs. The AD-SVF cells are simply isolated and injected into the patient without a cell culture step. Compared with cultured BM-MSCs(Bone Marrow-derived Mesenchymal Stem Cells), this technique has the advantage of supplying cells in a short time period (48 hours), and it should be remembered that although there are a large number of nucleated cells retrieved from the adipose digest, only a small percentage of nucleated cells are stems cells. In humans, 0.7% to 5% of nucleated cells in the stromal vascular fraction are stem cells.
Cartilage injury/osteoarthritis
As mentioned above, AD-SVF cell application in an equine model of early OA failed to result in any detectable improvement in articular health. In fact, AD-SVF cells led to an increase in synovial fluid concentration of the proinflammatory cytokine tumor necrosis factor-alpha. In dogs,
two reports of improved clinical signs of OA after treatment have been published. In a double-blinded study assessing the yse of AD-SVF cells in the hip joint of dogs, examining veterinarians (but not dog owners) reported signs of clinical improvement. In a second, uncontrolled study using AD-SVF cells for elbow OA, veterinarians and, to a lesser extent, owners both reported improvements in clinical signs. The disparity in the clinical benefits noted by owners in these studies investigation the use of AD-SVF cells in OA is unclear but
perhaps suggests that any benefit of AD-SVF cell application can be seen only in more advanced cases of OA or that changes in lameness associated with elbow OA in comparison with those of hip OA are more easily perceived by owners.
You have to decide for your own dogs. You are the guarded angels to them.